You can get pretty fed up when the pounds pile on – even though you’re eating healthily, staying active, and doing your best to take care of yourself. We get it. So – what else can be the culprit? Can hormones cause weight gain like this?
Yes, they can.
Hormones and weight gain are closely linked because hormones control the messages your body sends – about hunger, fat storage, energy use, and even sleep.
When they fall out of balance, those signals can get scrambled, and your body starts to hold on to extra weight no matter what you do.
The good news is that when you restore the balance in your hormone system, your body usually begins to cooperate again.
So let’s look at what’s happening and how to solve it.
Can Hormones Cause Weight Gain? Here’s How They Affect Your Body
As we mentioned, your hormones are your body’s communication system. They tell your cells when to burn calories, when to store fat, and when to rest.
When this system works smoothly, your metabolism works well too.
Hormonal changes can happen to both men and women.
But when individual hormones get out of sync for any reason – maybe due to pregnancy, perimenopause, menopause, thyroid changes, or long-term stress – the messages don’t transmit properly.
That’s why you often find hormone imbalance and weight gain together. For example:
- Estrogen and progesterone influence where fat is stored. When estrogen drops, weight may collect around the abdomen.
- Thyroid hormones set your metabolic speed. Low levels can slow your body’s calorie-burning ability.
- Cortisol, your stress hormone, raises blood sugar and can increase cravings.
- Insulin helps control blood sugar, but high levels can push your body toward fat storage.
- Testosterone helps maintain muscle. Less of it can mean less calorie-burning muscle mass.
So you can stop feeling guilty if you’re doing everything else right. Hormone problems and weight gain are more to do with your biology than pure willpower.
And now you know that, you can start thinking about how to get your hormones back in balance! But first, here’s another question we get asked…
Can Hormones Cause Weight Gain and Fatigue at the Same Time?
Yes. The two often go hand in hand. When hormones such as thyroid, cortisol, or insulin drift out of balance, your energy levels take a hit. You may wake up tired, rely on caffeine to push through the day, and feel too exhausted to exercise in the evening.
This is why so many people ask, “Can hormones cause weight gain and fatigue?” When your metabolism slows and your energy drops, daily movement declines and you don’t use calories as efficiently.
You find yourself in a frustrating cycle: Fatigue limits your activity, and inactivity fuels further weight gain.
If that sounds familiar, remember you’re not lazy. Your hormones are sending mixed signals. But with proper medical guidance, you can restore both balance and energy.
So, here’s when and how to go about keeping your hormone messengers in order!
When to Ask for Help at a Weight Loss Clinic or Weight Loss Doctor in Dallas
If you’ve followed the best “healthy weight” advice of having balanced meals, consistent workouts, and a good sleep routine, it might be time to ask for professional support.
We talked about the best time to test here. If you’re struggling, you need to know why asap.
And at a weight loss clinic, your care starts with understanding the why behind the struggle.
We do this in a data-backed way. Your Stella Mattina weight loss doctor in Dallas will order precise testing to check thyroid, estrogen, progesterone, testosterone, and cortisol levels, rather than guessing based on symptoms.
This is what makes medical weight loss Dallas programs at Stella Mattina different from quick fixes or fad diets. They’re grounded in data.
Another Stella difference is that hormone testing is combined with practical lifestyle coaching. For example, you’ll learn how nutrition, stress management, and strength training can help bring your hormones back into balance.
That’s because weight loss becomes achievable and sustainable when you look at, and tackle, the root cause of your hormone imbalance.
But as we said, you may already be doing everything just fine. In which case, hormone replacement therapy may be the next option.
Which Hormone Replacement Therapy Is Best for Weight Loss?
That’s one of the most common questions we hear. And the answer depends on you. Your hormone levels, age, and overall health determine what kind of therapy will work best. There’s no single product or dose that suits everyone.
At Stella Mattina, we use BioTE bioidentical hormone therapy, which is designed to restore hormones to their optimal range using tiny plant-derived pellets placed just beneath your skin.
These gradually release hormones over time, keeping levels steady and avoiding the highs and lows that can happen with other forms of HRT.
So, which hormone replacement therapy is best for weight loss? The one that rebalances your body safely and naturally, monitored by experienced clinicians!
Our team reviews your blood work, symptoms, and progress, adjusting treatment as needed. Restoring equilibrium can help ease fatigue, stabilize your mood, and support your metabolism to work well again.
In other words, we address the hormone imbalance and weight gain that’s been holding you back.
Stella Mattina Can Intervene Professionally When Imbalanced Hormones Cause Weight Gain
If you’ve been wondering can hormones cause weight gain, and you’ve read this far, you know the answer is yes – but also that rebalancing is possible.
At Stella Mattina, we offer personalized care. Every patient’s journey is different, which is why this matters.
Our weight loss programs blend science, testing, and compassionate guidance to help you solve the weight gain problem that’s frustrating you every day. And you’ll start to feel better as soon as the hormone program kicks in.
Your progress isn’t left to chance. Our team reviews your blood work regularly and fine-tunes treatment to keep your hormones stable over time.
With your body’s chemistry supported rather than ignored, you’ll suddenly find weight loss feels less like a battle and more like you’ll finally achieve your target, sustainable weight.
Take the first step today. Make an appointment to find out what your hormone levels are, and – if that’s at the bottom of your weight issue – we’ll help you sort it out.
We offer same-day appointments. Why wait to feel better? Choose your location here.

Dr. Gonzalo Venegas
Gonzalo Venegas, MD is the Medical Director of Stella Mattina Health and a respected obstetrician-gynecologist with over four decades of service in the Dallas medical community. He has led the Department of Obstetrics and Gynecology at Methodist Dallas Medical Center and contributed to community health through his role on the Parkland Health & Hospital System Board. A dedicated mentor at UT Southwestern, Dr. Venegas is known for his leadership, compassion, and commitment to advancing women’s health and medical education.